tu parles anglais Sandra ?
Si oui, voici quelques liens que je viens de trouver :
http://www.springerlink.com/content/75113jj23g436683/Abstract Intravenous glucose therapy to mother prior to delivery significantly affects glucose and insulin homeostasis in fetus and newborn infants. Specifically, the infants show hyperglycemia,1–11 and hyperinsulinism at birth,3,8,10 and are predisposed to hypoglycemia in the first few hours of life.2,8,10,11 In this paper we have focussed attention on the clinical significance of these changes and suggest some remedial measures, in light of our own research
= Les perfusions intraveineuses faites à la mère avant la délivrance affectent significativement l'équilibre du glucose et de l'insuline chez les foetus et les nouveaux-nés.
Plus spécifiquement, les enfants ont montré de l'hyperglycéme et de l'hyperinsulinémie à la naissance et sont prédisposés à l'hypoglycémie durant les premières heures de vie.
Dans cet article, nous avons concentré l'attention sur les significations cliniques de ces changements et nous suggérons des mesures pour y remédier.
http://www3.interscience.wiley.com/journal/119566793/abstract?CRETRY=1&SRETRY=0Summary. The effects on the fetus of high doses of glucose given to the mother in labour to correct maternal ketonuria were investigated. Three groups of patients were compared: one group received 1 litre of 10% (w/v) glucose intravenously over 1 h, the second group received 1 litre of 0.9% sodium chloride solution intravenously over 1 h and the final group had no supplementary infusion. It was observed that whereas glucose administration rapidly corrected maternal ketonaemia, there was a significant fall in pH and a rise in lactate in fetal blood. These effects were not observed in the other two groups. It was concluded that the use of high doses of intravenous glucose in labour should be avoided.
résumé : les effets sur le foetus de hautes doses de glucose données à la mère en travail pour corriger la "ketonuria" (je ne connais pas le terme exact en français mais en gros c'est ce qui arrive quand on ne nous donne pas à manger !!!) maternelle ont été investigués.
3 groupes de patientes ont été comparées : 1 groupe a reçu 1 l de solution de glucose à 10% en intraveineuse pendant 1 heure, le 2e groupe a reçu 1 litre de solution de "sodium chloride" (sérum phy ?) en intraveineuse pendant 1 h et le dernier groupe n'a pas eu de perfusion.
Il a été observé que l'administration de glucose corrigeait rapidement la "ketonaemia" maternelle mais qu'il y avait une chûte significative du pH et une augmentation du lactate dans le sang foetal. Ces effets n'ont pas été observés sur les autres groupes.
Nous concluons que les hautes doses de glucose en intraveineuse durant le travail doivent être évitées.
http://www3.interscience.wiley.com/journal/119516447/abstractSummary. Maternal and umbilical cord serum sodium and osmolality were studied prospectively in 140 deliveries to investigate whether transplacental hyponatraemia, seen following oxytocin infusion during labour, was due to the antidiuretic effect of oxytocin or was secondary to the infusion of aqueous glucose used as a vehicle for oxytocin, or both. Forty-five women received oxytocin in aqueous glucose for induction or augmentation of labour (oxytocin group), 43 received aqueous glucose infusion alone (glucose group) and 52 did not receive any intravenous infusions (control group). Mean cord sodium levels were significantly lower in the oxytocin (131·4, SD 3·6 mmol/l) and glucose groups (132·5, SD 3·2 mmol/l) than in the control group (135·0, SD 3·0 mmol/l). Hyponatraemia (Na <130 mmol) was seen in 47% and 30% of the infants in the oxytocin and glucose groups respectively, in contrast to only 5.8% of the infants in the control group. Significant negative linear correlations were seen between serum sodium and the dose of oxytocin (P<0·01) and log of the volume of glucose solution infused (P<0·001). The hyponatraemic newborn infants had a significantly higher incidence of transient neonatal tachypnea (7/37, 19%) than the normonatraemic infants (2%). Our results strongly suggest that infusion of oxytocin and glucose both cause maternal and transplacental hyponatraemia, even in recommended doses. This should be taken in account while planning a safe dose of oxytocin and glucose for infusion during labour.
Bon je traduis plus c'est trop long
...
si tu veux en chercher d'autre, tu peux chercher avec les mots clés : glucose infusion during labour
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Mer 25 Mar 2020 - 16:46 par capucine
